Diabetes is strongly related to metabolic syndrome, in most cases, the occurrence of type 2 diabetes affirms that a person is developing metabolic syndrome. The findings of this thesis show that the majority of. Effect of exercise training on metabolic syndrome zscore. Insulin resistance is thought to be a key underlying. Obesity is a risk factor for morbidity and mortality from cardiovascular, musculoskeletal, malignant and metabolic diseases, 1 as well as considerable social and financial burdens. Metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2. Introduction etabolic syndrome is a cluster of cardiovascular risk factor associated with. An examination of treatment, survival, and access to care, cassie lewis. Androgen deprivation therapy adt, metabolic syndrome and. Adults by jennifer saylor dissertation submitted to the faculty of the graduate school of the university of maryland baltimore in partial fulfillment of the requirements for the degree of doctor of philosophy 2011. Metabolic syndrome in hospitalised psoriatic patients diploma thesis academic year. The relationship between diabetes, metabolic syndrome, and platelet activity as measured by mean platelet volume the national health and nutrition examination survey, 19992004 binita shah, md. Mar 07, 2011 march 8, 2011 the mediterranean diet is known to help prevent heart disease.
The digital thesis deposit has been a graduation requirement since 2006. Timothy garvey md, cristina laracastro md, phd, in handbook of clinical nutrition fourth edition, 2006. You will be the only person to ever receive our original, specialized document on metabolic syndrome x, which we will write. Edington, chair professor alfred franzblau associate professor david j. The metabolic syndrome robert h eckel, scott m grundy, paul z zimmet the metabolic syndrome is a common metabolic disorder that results from the increasing prevalence of obesity. Shi j, finckenberg, p, martonen e, ahlrooslehmus a, pilvi t, korpela r, mervaala e 2012 metabolic effects of lactoferrin during energy restriction and weight.
Novel biomarkers associated with gestational diabetes. The metabolic and environmental determinants of obesity in. Insulin resistance is thought to be a key underlying feature of pcos, but its role in metabolic and reproductive complications associated with the syndrome remains elusive. As a systemic metabolic disorder, obesity affects many organ systems and has a complex etiology. It examines the impact of androgen deprivation therapy, its association with metabolic syndrome and prostate cancer progression, and the therapeutic and metabolic benefits of. Metabolic syndrome research share this at the center of the obesity epidemic is the metabolic syndrome a cluster of conditions defined by excess body weight and the dysregulated processing of sugar and. This complexity lies in several aspects, but the majority of obstacles and challenges in mets. The prevalence of metabolic syndrome is increasing throughout the world.
May 31, 2018 phd thesis, queensland university of technology. Metabolic changes in chronic fatigue syndrome thesis submitted for the degree of doctor of philosophy ph d in the faculty of medicine university of glasgow abhijit chaudhuri dm md facp. Population aging is accompanied by higher prevalence of ms. Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male zdf rats. A panel for early detection, management, and risk stratification in the west virginian population krithika srikanthan 1, andrew feyh, haresh. Although it is a feature commonly associated with the development of type 2 diabetes may also be a characteristic of. Association between vitamin d and metabolic syndrome in older. The findings of this thesis show that the majority of urban black south african. Prevalence of metabolic syndrome in elderly and agreement. Essential for the development of metabolic syndrome seems to be the presence of increased insulin resistance. Metabolic syndrome and workplace outcomes by alyssa belaire schultz a dissertation submitted in partial fulfillment of the requirements for the degree of doctor of philosophy. In one study, the presence of four or more metabolic syndrome risk factors was associated with a 3. Szilvia bokor department of paediatrics, medical faculty, university of pecs programme leader.
The paper that has been published constitutes chapter 2 of this thesis. Metabolic syndrome and workplace outcomes by alyssa belaire schultz a dissertation submitted in partial fulfillment of the requirements for the degree of doctor of philosophy kinesiology in the university of michigan 2009 doctoral committee. Metabolic syndrome an overview sciencedirect topics. Phd thesis bioactive compounds, antioxidant activity and quality of plum and sweet cherry cultivars as affected by ripening ontree, cold storage and postharvest treatments phd. A retrospective cohort study in south carolina, iffat nahar. Recently, low serum concentrations of 25hydroxyvitamin d 25ohd have been linked to disturbances in glucose metabolism, development of type 2 diabetes, and increased risk of metabolic syndrome. The current trends of rising obesity and low vitamin d levels within the u. Obesity and metabolic syndrome in an ageing cohort of black women living in soweto, johannesburg study of women in and entering endocrine transition sweet philippe jeanluc gradidge student number. March 8, 2011 the mediterranean diet is known to help prevent heart disease. Metabolic syndrome has been identified by central obesity. Chaudhuri, abhijit 2003 metabolic changes in chronic fatigue syndrome. Metabolic syndrome research share this at the center of the obesity epidemic is the metabolic syndrome a cluster of conditions defined by excess body weight and the dysregulated processing of sugar and lipids fats and cholesterol. The research presented in this thesis examines the effectiveness of two commonly used antiobesity botanical extracts, namely caralluma fimbriata and citrus sinensis moro variety.
This phd project was part of the lean seafood in the prevention of the metabolic syndrome. Metabolic syndrome and pregnancy, its prevalence, obstetrical. Metabolic syndrome, metabolic syndrome zscore, c reactive protein. In vivo role of jak2 in the pathogenesis of obesity and the. Obese children and adolescents demonstrated very low levels of physical activity, reduced cardiorespiratory fitness and significant psychological impairments. The papers have not earlier been part of a phd dissertation or other theses. A version of the paper as it appears in the journal is in the appendix d. Metabolic syndrome is the name for a group of risk factors for heart disease, diabetes, and other health problems. This thesis explored these determinants with particular reference to the role of physical activity, dietary intake and cardiorespiratory fitness. Polycystic ovary syndrome pcos is a common and complex reproductive and metabolic condition with major health consequences across the lifespan. Sukumar, nithya 2017 novel biomarkers associated with gestational diabetes mellitus and metabolic outcomes of pregnancy. Mechanisms linking obesity to its complications are poorly understood. Obesity and the metabolic syndrome represent a serious global public health issue due to their longterm complications including type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular disease and some cancers.
Shi j, finckenberg, p, martonen e, ahlrooslehmus a, pilvi t, korpela r, mervaala e 2012 metabolic effects of lactoferrin during energy restriction and weight regain in dietinduced. Yale medicine thesis digital library school of medicine. The relationship between diabetes, metabolic syndrome, and. If you require help with your dissertation, masters thesis, phd research proposal, or any other kind of sample assignment involving metabolic syndrome x, our contracted research professionals can. Systems biology of metabolic syndrome development and. University of massachusetts graduate school of biomedical sciences, worcester. Effect of heart rate variability biofeedback on sleep, joshua mercadel. Introduction etabolic syndrome is a cluster of cardiovascular risk factor associated with increased risk of cardiovascular disease and diabetes mellitus1. The primary aim of this phd project was to investigate the efficacy of c.
Essential for the development of metabolic syndrome seems to be the presence of increased insulin. The number of metabolic syndrome components also influences the degree of risk. Adverse birth outcomes among women with physical disabilities. In vivo role of jak2 in the pathogenesis of obesity and. Systems biology of metabolic syndrome development and treatment.
Epidemiology and biostatistics theses and dissertations. Metabolic syndrome in patients with firstepisode schizophrenia 2 this phd dissertation is based on the three papers. Mediterranean diet lowers risk of metabolic syndrome. Metabolic syndrome ms is an aggregation of risk factors that increase the incidence of cardiovascular events and diabetes mellitus dm. Student huertas maria diazmula, msc supervisors professor maria serrano, phd professor daniel valero, phd orihuela, may 2011. Disparities in nonsmall cell lung cancer in the united states. Association between vitamin d and metabolic syndrome in older adults by allison hedges a thesis submitted to the graduate faculty in partial fulfillment of the requirements for the degree of master of science major. You can have just one risk factor, but people often have several of them together. This thesis describes a translational research approach to identifying a cancer mechanism driven by metabolic syndrome. University of split school of medicine zrinka visakcagalj. In brazil, a phd thesis developed in the pg program in gynecology, obstetrics and mastology pggom at unesp by negrato et al. Starting in 2012, alumni of the yale school of medicine were invited to participate in the ymtdl project by granting scanning and.
Cardioprotective and hepatoprotective effects of natural. If you require help with your dissertation, masters thesis, phd research proposal, or any other kind of sample assignment involving metabolic syndrome x, our contracted research professionals can begin helping today. My official followup group, professor ulla rajala, md, phd and professor jouni lohi md, phd are warmly thanked for their guidance. Metabolic syndrome is the clustering of risk factors for cardiovascular disease and type 2 diabetes. Now new research extends these benefits to metabolic syndrome, a cluster of risk factors that includes high. Metabolic syndrome mets represents a cluster of metabolic abnormalities that include hypertension, central obesity, insulin resistance, and atherogenic dyslipidemia, and is strongly associated with an increased risk for developing diabetes and atherosclerotic and nonatherosclerotic cardiovascular disease cvd.
A panel for early detection, management, and risk stratification in the west virginian population krithika srikanthan 1, andrew feyh, haresh visweshwar, joseph i. The disorder is defined in various ways, but in the near future a new definitions. Polycystic ovary syndrome, obesity and insulin resistance. He patiently corrected my writing and mentally supported my research. Association between vitamin d and metabolic syndrome in. University of split school of medicine zrinka visak. In the dissertation they are referred to as paper i, ii and iii. The number of metabolic syndrome components also influences the degree of. Metabolic syndrome, also known as insulin resistance syndrome irs and syndrome.
This complexity lies in several aspects, but the majority of obstacles and. Population aging is accompanied by higher prevalence of ms, which varies depending on the population studied and the diagnostic criteria used. Metabolic syndrome and workplace outcomes by a dissertation. The associations of the metabolic syndrome and body adiposity with the progression of preclinical carotid atherosclerosis, and the associations of lowgrade inflammation with the metabolic syndrome were evaluated in a 12year followup study of elderly women, 70 to 80 years of age at the end of the followup. Abstract the metabolic syndromeotherwise called syndrome x, insulin resistance syndrome, reaven syndrome, and the deadly quartet is the name given to the aggregate of clinical conditions. D study and related research, as well as his patience, caring, motivation, and immense knowledge inhelping me design the research project. The metabolic and environmental determinants of obesity in childhood. Chaudhuri, abhijit 2003 metabolic changes in chronic fatigue. Complex roles of macrophages in lipid metabolism and.
Their wise and constructive comments helped me to improve the thesis. Metabolic syndrome and physical activity in patients with. Metabolic syndrome, also known as insulin resistance syndrome irs and syndrome x, is a cluster of metabolic and anthropometric traits including glucose intolerance, upper body fat distribution increased intraabdominal fat mass, hypertension, dysfibrinolysis, and a dyslipidemia. The metabolic syndrome is a common metabolic disorder that results from the increasing prevalence of obesity. When you have at least three of them, it is called metabolic syndrome. Association between vitamin d and metabolic syndrome in older adults by allison hedges a thesis submitted to the graduate faculty in partial fulfillment of the requirements for the degree of master. Edwards school of medicine, marshall university, usa 2. Now new research extends these benefits to metabolic syndrome, a cluster of risk factors that includes high blood. Metabolic changes in chronic fatigue syndrome enlighten. Sharp, major professor matthew rowling mack shelley.