Edington, chair professor alfred franzblau associate professor david j. The biopsychosocial model of metabolic syndrome among u. Effect of heart rate variability biofeedback on sleep, joshua mercadel. Metabolic syndrome is the clustering of risk factors for cardiovascular disease and type 2 diabetes. Metabolic syndrome and physical activity in patients with. Metabolic changes in chronic fatigue syndrome thesis submitted for the degree of doctor of philosophy ph d in the faculty of medicine university of glasgow abhijit chaudhuri dm md facp. Diabetes is strongly related to metabolic syndrome, in most cases, the occurrence of type 2 diabetes affirms that a person is developing metabolic syndrome.
In brazil, a phd thesis developed in the pg program in gynecology, obstetrics and mastology pggom at unesp by negrato et al. Timothy garvey md, cristina laracastro md, phd, in handbook of clinical nutrition fourth edition, 2006. Prevalence of metabolic syndrome in elderly and agreement. Shi j, finckenberg, p, martonen e, ahlrooslehmus a, pilvi t, korpela r, mervaala e 2012 metabolic effects of lactoferrin during energy restriction and weight. This thesis explored these determinants with particular reference to the role of physical activity, dietary intake and cardiorespiratory fitness. An examination of treatment, survival, and access to care, cassie lewis. Starting in 2012, alumni of the yale school of medicine were invited to participate in the ymtdl project by granting scanning and. Introduction etabolic syndrome is a cluster of cardiovascular risk factor associated with increased risk of cardiovascular disease and diabetes mellitus1. Mediterranean diet lowers risk of metabolic syndrome. Mar 07, 2011 march 8, 2011 the mediterranean diet is known to help prevent heart disease. Systems biology of metabolic syndrome development and treatment. This thesis describes a translational research approach to identifying a cancer mechanism driven by metabolic syndrome. Association between vitamin d and metabolic syndrome in older adults by allison hedges a thesis submitted to the graduate faculty in partial fulfillment of the requirements for the degree of master. Metabolic syndrome in hospitalised psoriatic patients diploma thesis academic year.
Metabolic syndrome and workplace outcomes by alyssa belaire schultz a dissertation submitted in partial fulfillment of the requirements for the degree of doctor of philosophy. Metabolic changes in chronic fatigue syndrome enlighten. Obesity is a risk factor for morbidity and mortality from cardiovascular, musculoskeletal, malignant and metabolic diseases, 1 as well as considerable social and financial burdens. Cardioprotective and hepatoprotective effects of natural. Obese children and adolescents demonstrated very low levels of physical activity, reduced cardiorespiratory fitness and significant psychological impairments. Association between vitamin d and metabolic syndrome in older. Now new research extends these benefits to metabolic syndrome, a cluster of risk factors that includes high blood.
Chaudhuri, abhijit 2003 metabolic changes in chronic fatigue syndrome. Disparities in nonsmall cell lung cancer in the united states. Metabolic syndrome ms is an aggregation of risk factors that increase the incidence of cardiovascular events and diabetes mellitus dm. Polycystic ovary syndrome, obesity and insulin resistance. The primary aim of this phd project was to investigate the efficacy of c. The current trends of rising obesity and low vitamin d levels within the u. Sharp, major professor matthew rowling mack shelley.
Sukumar, nithya 2017 novel biomarkers associated with gestational diabetes mellitus and metabolic outcomes of pregnancy. The metabolic and environmental determinants of obesity in. The metabolic syndrome robert h eckel, scott m grundy, paul z zimmet the metabolic syndrome is a common metabolic disorder that results from the increasing prevalence of obesity. Metabolic syndrome research share this at the center of the obesity epidemic is the metabolic syndrome a cluster of conditions defined by excess body weight and the dysregulated processing of sugar and. Systems biology of metabolic syndrome development and. The prevalence of metabolic syndrome is increasing throughout the world. Edwards school of medicine, marshall university, usa 2. Association between vitamin d and metabolic syndrome in older adults by allison hedges a thesis submitted to the graduate faculty in partial fulfillment of the requirements for the degree of master of science major. Insulin resistance is thought to be a key underlying feature of pcos, but its role in metabolic and reproductive complications associated with the syndrome remains elusive. Association between vitamin d and metabolic syndrome in. May 31, 2018 phd thesis, queensland university of technology. This phd project was part of the lean seafood in the prevention of the metabolic syndrome. You can have just one risk factor, but people often have several of them together.
The metabolic and environmental determinants of obesity in childhood. Yale medicine thesis digital library school of medicine. Androgen deprivation therapy adt, metabolic syndrome and. Metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2. A retrospective cohort study in south carolina, iffat nahar. University of split school of medicine zrinka visak. Mechanisms linking obesity to its complications are poorly understood.
Obesity and the metabolic syndrome represent a serious global public health issue due to their longterm complications including type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular disease and. Metabolic syndrome and workplace outcomes by alyssa belaire schultz a dissertation submitted in partial fulfillment of the requirements for the degree of doctor of philosophy kinesiology in the university of michigan 2009 doctoral committee. In vivo role of jak2 in the pathogenesis of obesity and. Although it is a feature commonly associated with the development of type 2 diabetes may also be a characteristic of.
The relationship between diabetes, metabolic syndrome, and platelet activity as measured by mean platelet volume the national health and nutrition examination survey, 19992004 binita shah, md. Metabolic syndrome, also known as insulin resistance syndrome irs and syndrome x, is a cluster of metabolic and anthropometric traits including glucose intolerance, upper body fat distribution increased intraabdominal fat mass, hypertension, dysfibrinolysis, and a dyslipidemia. It examines the impact of androgen deprivation therapy, its association with metabolic syndrome and prostate cancer progression, and the therapeutic and metabolic benefits of. Recently, low serum concentrations of 25hydroxyvitamin d 25ohd have been linked to disturbances in glucose metabolism, development of type 2 diabetes, and increased risk of metabolic syndrome.
In one study, the presence of four or more metabolic syndrome risk factors was associated with a 3. Metabolic syndrome mets represents a cluster of metabolic abnormalities that include hypertension, central obesity, insulin resistance, and atherogenic dyslipidemia, and is strongly associated with an increased risk for developing diabetes and atherosclerotic and nonatherosclerotic cardiovascular disease cvd. If you require help with your dissertation, masters thesis, phd research proposal, or any other kind of sample assignment involving metabolic syndrome x, our contracted research professionals can. The papers have not earlier been part of a phd dissertation or other theses. The digital thesis deposit has been a graduation requirement since 2006. D study and related research, as well as his patience, caring, motivation, and immense knowledge inhelping me design the research project. Effect of exercise training on metabolic syndrome zscore. A panel for early detection, management, and risk stratification in the west virginian population krithika srikanthan 1, andrew feyh, haresh visweshwar, joseph i.
Chaudhuri, abhijit 2003 metabolic changes in chronic fatigue. The number of metabolic syndrome components also influences the degree of risk. A panel for early detection, management, and risk stratification in the west virginian population krithika srikanthan 1, andrew feyh, haresh. Population aging is accompanied by higher prevalence of ms, which varies depending on the population studied and the diagnostic criteria used. Novel biomarkers associated with gestational diabetes. Obesity and metabolic syndrome in an ageing cohort of black women living in soweto, johannesburg study of women in and entering endocrine transition sweet philippe jeanluc gradidge student number. You will be the only person to ever receive our original, specialized document on metabolic syndrome x, which we will write. When you have at least three of them, it is called metabolic syndrome. Population aging is accompanied by higher prevalence of ms. The research presented in this thesis examines the effectiveness of two commonly used antiobesity botanical extracts, namely caralluma fimbriata and citrus sinensis moro variety. Student huertas maria diazmula, msc supervisors professor maria serrano, phd professor daniel valero, phd orihuela, may 2011.
In the dissertation they are referred to as paper i, ii and iii. Metabolic syndrome and pregnancy, its prevalence, obstetrical. In vivo role of jak2 in the pathogenesis of obesity and the. University of massachusetts graduate school of biomedical sciences, worcester. Metabolic syndrome, also known as insulin resistance syndrome irs and syndrome. Abstract the metabolic syndromeotherwise called syndrome x, insulin resistance syndrome, reaven syndrome, and the deadly quartet is the name given to the aggregate of clinical conditions. Metabolic syndrome an overview sciencedirect topics. Adults by jennifer saylor dissertation submitted to the faculty of the graduate school of the university of maryland baltimore in partial fulfillment of the requirements for the degree of doctor of philosophy 2011. Metabolic syndrome, metabolic syndrome zscore, c reactive protein. Metabolic syndrome in patients with firstepisode schizophrenia 2 this phd dissertation is based on the three papers. Complex roles of macrophages in lipid metabolism and. Now new research extends these benefits to metabolic syndrome, a cluster of risk factors that includes high.
Their wise and constructive comments helped me to improve the thesis. Introduction etabolic syndrome is a cluster of cardiovascular risk factor associated with. Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male zdf rats. Metabolic syndrome and workplace outcomes by a dissertation. The paper that has been published constitutes chapter 2 of this thesis. Metabolic syndrome is the name for a group of risk factors for heart disease, diabetes, and other health problems. Metabolic syndrome research share this at the center of the obesity epidemic is the metabolic syndrome a cluster of conditions defined by excess body weight and the dysregulated processing of sugar and lipids fats and cholesterol. This complexity lies in several aspects, but the majority of obstacles and. The relationship between diabetes, metabolic syndrome, and. This complexity lies in several aspects, but the majority of obstacles and challenges in mets.
The metabolic syndrome is a common metabolic disorder that results from the increasing prevalence of obesity. Obesity and the metabolic syndrome represent a serious global public health issue due to their longterm complications including type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular disease and some cancers. Phd thesis bioactive compounds, antioxidant activity and quality of plum and sweet cherry cultivars as affected by ripening ontree, cold storage and postharvest treatments phd. Epidemiology and biostatistics theses and dissertations. March 8, 2011 the mediterranean diet is known to help prevent heart disease.
University of split school of medicine zrinka visakcagalj. If you require help with your dissertation, masters thesis, phd research proposal, or any other kind of sample assignment involving metabolic syndrome x, our contracted research professionals can begin helping today. As a systemic metabolic disorder, obesity affects many organ systems and has a complex etiology. The findings of this thesis show that the majority of. Essential for the development of metabolic syndrome seems to be the presence of increased insulin. The associations of the metabolic syndrome and body adiposity with the progression of preclinical carotid atherosclerosis, and the associations of lowgrade inflammation with the metabolic syndrome were evaluated in a 12year followup study of elderly women, 70 to 80 years of age at the end of the followup. Adverse birth outcomes among women with physical disabilities. The number of metabolic syndrome components also influences the degree of. My official followup group, professor ulla rajala, md, phd and professor jouni lohi md, phd are warmly thanked for their guidance. A version of the paper as it appears in the journal is in the appendix d. Shi j, finckenberg, p, martonen e, ahlrooslehmus a, pilvi t, korpela r, mervaala e 2012 metabolic effects of lactoferrin during energy restriction and weight regain in dietinduced. The disorder is defined in various ways, but in the near future a new definitions.
Metabolic syndrome has been identified by central obesity. The findings of this thesis show that the majority of urban black south african. Insulin resistance is thought to be a key underlying. He patiently corrected my writing and mentally supported my research. Szilvia bokor department of paediatrics, medical faculty, university of pecs programme leader. Polycystic ovary syndrome pcos is a common and complex reproductive and metabolic condition with major health consequences across the lifespan. Essential for the development of metabolic syndrome seems to be the presence of increased insulin resistance.